Dimethyl fumarate eliminates differentially culturable Mycobacterium tuberculosis in an intranasal murine model of tuberculosis

Dimethyl fumarate eliminates differentially culturable Mycobacterium tuberculosis in an intranasal murine model of tuberculosis

Tuberculosis (TB) claims nearly 1.5 million lives annually. Current TB treatment requires a combination of several drugs administered for at least 6 months. Mycobacterium tuberculosis (Mtb), the causative agent of TB, can persist in infected humans and animals for decades. Moreover, during infection...

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Bibliographic Details
Main Authors: Sarah M. Glenn, Obolbek Turapov, Vadim Makarov, Douglas B. Kell, Galina V. Mukamolova
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Mycobacterium tuberculosis
tuberculosis
differentially culturable bacteria
treatment
persisters
resuscitation-promoting factor
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.957287/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2022.957287/full

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