Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations

Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 provides a highly efficient and flexible genome editing technology with numerous potential applications ranging from gene therapy to population control. Some proposed applications involve the integration of CRISPR/Cas9 endonucle...

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Bibliographic Details
Main Authors: Anna M Langmüller, Jackson Champer, Sandra Lapinska, Lin Xie, Matthew Metzloff, Samuel E Champer, Jingxian Liu, Yineng Xu, Jie Du, Andrew G Clark, Philipp W Messer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-09-01
Series:eLife
Subjects:
gene drive
fitness
off-target effects
CRISPR
Online Access:https://elifesciences.org/articles/71809

Internet

https://elifesciences.org/articles/71809

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