Impact of structural modifications of IgG antibodies on effector functions

Impact of structural modifications of IgG antibodies on effector functions

Immunoglobulin G (IgG) antibodies are a critical component of the adaptive immune system, binding to and neutralizing pathogens and other foreign substances. Recent advances in molecular antibody biology and structural protein engineering enabled the modification of IgG antibodies to enhance their t...

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Bibliographic Details
Main Authors: Timon Damelang, Maximilian Brinkhaus, Thijs L. J. van Osch, Janine Schuurman, Aran F. Labrijn, Theo Rispens, Gestur Vidarsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
antibodies
IgG
subclasses
allotypes
glycosylation
FcγR
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1304365/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1304365/full

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