No neuroprotective effect of therapeutic hypothermia following lipopolysaccharide-sensitized hypoxia-ischemia: a newborn piglet study

No neuroprotective effect of therapeutic hypothermia following lipopolysaccharide-sensitized hypoxia-ischemia: a newborn piglet study

IntroductionTherapeutic hypothermia is the only proven neuroprotective treatment for hypoxic-ischemic encephalopathy. However, studies have questioned whether therapeutic hypothermia may benefit newborns subjected to infection or inflammation before a hypoxic-ischemic insult. We aimed to compare new...

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Bibliographic Details
Main Authors: Mads Andersen, Hannah Brogård Andersen, Ted Carl Kejlberg Andelius, Lærke Hjøllund Hansen, Regitze Pinnerup, Mette Bjerre, Steffen Ringgaard, Leslie Schwendimann, Pierre Gressens, Kasper Jacobsen Kyng, Tine Brink Henriksen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pediatrics
Subjects:
hypoxic-ischemic encephalopathy
lipopolysaccharide
therapeutic hypothermia
neuroprotection
animal model
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1268237/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2023.1268237/full

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