Longitudinal analysis of influenza vaccination implicates regulation of RIG-I signaling by DNA methylation
Abstract Influenza virus infection alters the promoter DNA methylation of key immune response-related genes, including type-1 interferons and proinflammatory cytokines. However, less is known about the effect of the influenza vaccine on the epigenome. We utilized a targeted DNA methylation approach...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-01-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-51665-9 |