Structural and Functional Characterization of Four Novel Fibrinogen Mutations in <i>FGB</i> Causing Congenital Fibrinogen Disorder
Congenital fibrinogen disorders are caused by mutations in genes coding for fibrinogen and may lead to various clinical phenotypes. Here, we present a functional and structural analysis of 4 novel variants located in the <i>FGB</i> gene coding for fibrinogen Bβ chain-heterozygous missens...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-01-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/23/2/721 |