Epigenetic signatures relating to disease-associated genotypic burden in familial risk of bipolar disorder

Abstract Environmental factors contribute to risk of bipolar disorder (BD), but how environmental factors impact the development of psychopathology within the context of elevated genetic risk is unknown. We herein sought to identify epigenetic signatures operating in the context of polygenic risk fo...

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Bibliographic Details
Main Authors: Sonia Hesam-Shariati, Bronwyn J. Overs, Gloria Roberts, Claudio Toma, Oliver J. Watkeys, Melissa J. Green, Kerrie D. Pierce, Howard J. Edenberg, Holly C. Wilcox, Emma K. Stapp, Melvin G. McInnis, Leslie A. Hulvershorn, John I. Nurnberger, Peter R. Schofield, Philip B. Mitchell, Janice M. Fullerton
Format: Article
Language:English
Published: Nature Publishing Group 2022-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-02079-6