N-Aminopyridinium reagents as traceless activating groups in the synthesis of N-Aryl aziridines

N-Aminopyridinium reagents as traceless activating groups in the synthesis of N-Aryl aziridines

Aziridines are useful intermediates, present in important synthetic targets. Here, the authors show a strategy for the synthesis of N-aryl aziridines based on N-aminopyridinium reagents followed by Ni-catalyzed C–N cross-coupling of N-pyridinium aziridines with aryl boronic acids.

Bibliographic Details
Main Authors: Hao Tan, Samya Samanta, Asim Maity, Pritam Roychowdhury, David C. Powers
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31032-w

Internet

https://doi.org/10.1038/s41467-022-31032-w

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