Reduced stability and increased dynamics in the human proliferating cell nuclear antigen (PCNA) relative to the yeast homolog.

Reduced stability and increased dynamics in the human proliferating cell nuclear antigen (PCNA) relative to the yeast homolog.

Proliferating Cell Nuclear Antigen (PCNA) is an essential factor for DNA replication and repair. PCNA forms a toroidal, ring shaped structure of 90 kDa by the symmetric association of three identical monomers. The ring encircles the DNA and acts as a platform where polymerases and other proteins doc...

Full description

Bibliographic Details
Main Authors: Alfredo De Biasio, Ricardo Sánchez, Jesús Prieto, Maider Villate, Ramón Campos-Olivas, Francisco J Blanco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3041752?pdf=render

Internet

http://europepmc.org/articles/PMC3041752?pdf=render

Similar Items