Depression accelerates gastric cancer invasion and metastasis by inducing a neuroendocrine phenotype via the catecholamine/β2‐AR/MACC1 axis

Depression accelerates gastric cancer invasion and metastasis by inducing a neuroendocrine phenotype via the catecholamine/β2‐AR/MACC1 axis

Abstract Background Depression is a common, easily ignored, accompanied disease of gastric cancer (GC) patients and is often observed with elevated plasma catecholamine levels. Depression frequently promotes GC progression and leads to poor clinical outcomes; however, the molecular mechanisms underl...

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Bibliographic Details
Main Authors: Changqie Pan, Jianhua Wu, Siting Zheng, Huiying Sun, Yisheng Fang, Zhenhua Huang, Min Shi, Li Liang, Jianping Bin, Yulin Liao, Jinzhang Chen, Wangjun Liao
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Cancer Communications
Subjects:
catecholamines
depression
gastric cancer
MACC1
neuroendocrine phenotype
psychological stress
Online Access:https://doi.org/10.1002/cac2.12198

Internet

https://doi.org/10.1002/cac2.12198

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