Harnessing MerTK agonism for targeted therapeutics

Phagocytosis plays important roles both in homeostasis and under pathological conditions. Fcγ receptor-mediated phagocytosis has been exploited as an integral mechanism for antibody-based therapies. Unlike Fcγ receptor-mediated phagocytosis, MerTK-mediated phagocytic clearance is immunologically sil...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Vivekananda Kedage, Diego Ellerman, Yongmei Chen, Wei-Ching Liang, Joven Borneo, Yan Wu, Minhong Yan
التنسيق: مقال
اللغة:English
منشور في: Taylor & Francis Group 2020-01-01
سلاسل:mAbs
الموضوعات:
الوصول للمادة أونلاين:https://www.tandfonline.com/doi/10.1080/19420862.2019.1685832