Dysbindin deficiency Alters Cardiac BLOC-1 Complex and Myozap Levels in Mice

Dysbindin deficiency Alters Cardiac BLOC-1 Complex and Myozap Levels in Mice

Dysbindin, a schizophrenia susceptibility marker and an essential constituent of BLOC-1 (biogenesis of lysosome-related organelles complex-1), has recently been associated with cardiomyocyte hypertrophy through the activation of Myozap-RhoA-mediated SRF signaling. We employed sandy mice (<i>Dt...

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Bibliographic Details
Main Authors: Ankush Borlepawar, Nesrin Schmiedel, Matthias Eden, Lynn Christen, Alexandra Rosskopf, Derk Frank, Renate Lüllmann-Rauch, Norbert Frey, Ashraf Yusuf Rangrez
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cells
Subjects:
Dysbindin
cardiac hypertrophy
Myozap
Pallidin
Muted
Online Access:https://www.mdpi.com/2073-4409/9/11/2390

Internet

https://www.mdpi.com/2073-4409/9/11/2390

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