Impact of genetic background on allele selection in a highly mutable Candida albicans gene, PNG2.

In many microbes rapid mutation of highly mutable contingency genes continually replenishes a pool of variant alleles from which the most suitable are selected, assisting in rapid adaptation and evasion of the immune response. In some contingency genes mutability is achieved through DNA repeats with...

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Bibliographic Details
Main Authors: Ningxin Zhang, Richard D Cannon, Barbara R Holland, Mark L Patchett, Jan Schmid
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20231904/pdf/?tool=EBI