Alteration of neurofilament heavy chain and its phosphoforms reveals early subcellular damage beyond the optic nerve head in glaucoma

Alteration of neurofilament heavy chain and its phosphoforms reveals early subcellular damage beyond the optic nerve head in glaucoma

BackgroundRetinal ganglion cells (RGCs) axon loss at the site of optic nerve head (ONH) is long believed as the common pathology in glaucoma since different types of glaucoma possessing different characteristic of intraocular pressure, and this damage was only detected at the later stage.MethodsTo a...

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Bibliographic Details
Main Authors: Lan Zhou, Dongyue Lin, Guihua Xu, Xiaoyi Wang, Zilin Chen, Dingding Wang, Huiya Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Neurology
Subjects:
neurofilament heavy chain
optic nerve head
retinal ganglion cells
axon degeneration
acute angle closed glaucoma
chronic angle closed glaucoma
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1091697/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2023.1091697/full

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