Visualization of protein folding funnels in lattice models.

Protein folding occurs in a very high dimensional phase space with an exponentially large number of states, and according to the energy landscape theory it exhibits a topology resembling a funnel. In this statistical approach, the folding mechanism is unveiled by describing the local minima in an ef...

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Bibliographic Details
Main Authors: Antonio B Oliveira, Francisco M Fatore, Fernando V Paulovich, Osvaldo N Oliveira, Vitor B P Leite
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4091862?pdf=render