Adrenomedullin has a cytoprotective role against endoplasmic reticulum stress for pancreatic β‐cells in autocrine and paracrine manners

Adrenomedullin has a cytoprotective role against endoplasmic reticulum stress for pancreatic β‐cells in autocrine and paracrine manners

Abstract Aims/Introduction Pancreatic β‐cells are sensitive to endoplasmic reticulum (ER) stress, which has a major role in the context of β‐cell death. Adrenomedullin (ADM) has been shown to exert a cytoprotective effect under various pathophysiological conditions. Several studies have suggested th...

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Bibliographic Details
Main Authors: Risa Suetomi, Yasuharu Ohta, Masaru Akiyama, Takuro Matsumura, Akihiko Taguchi, Kaoru Yamamoto, Takashi Kamatani, Yukio Tanizawa
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Journal of Diabetes Investigation
Subjects:
Adrenomedullin
Apoptosis
Pancreatic islet
Online Access:https://doi.org/10.1111/jdi.13218

Internet

https://doi.org/10.1111/jdi.13218

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