Analysis of Actin and Focal Adhesion Organisation in U2OS Cells on Polymer Nanostructures

Abstract Background In this work, we explore how U2OS cells are affected by arrays of polymer nanopillars fabricated on flat glass surfaces. We focus on describing changes to the organisation of the actin cytoskeleton and in the location, number and shape of focal adhesions. From our findings we ide...

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Bibliographic Details
Main Authors: Jakob B. Vinje, Noemi Antonella Guadagno, Cinzia Progida, Pawel Sikorski
Format: Article
Language:English
Published: SpringerOpen 2021-09-01
Series:Nanoscale Research Letters
Subjects:
Online Access:https://doi.org/10.1186/s11671-021-03598-9