Sevoflurane Increases Hippocampal Theta Oscillations and Impairs Memory Via TASK-3 Channels

Sevoflurane can induce memory impairment during clinical anesthesia; however, the underlying mechanisms are largely unknown. TASK-3 channels are one of the potential targets of sevoflurane. Accumulating evidence supports a negative role of intracranial theta rhythms (4–12 Hz) in memory formation. He...

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Bibliographic Details
Main Authors: Linlin Han, Shuai Zhao, Feng Xu, Yafeng Wang, Ruihui Zhou, Shiqian Huang, Yuanyuan Ding, Daling Deng, Weike Mao, Xiangdong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.728300/full