Population-specific positive selection on low CR1 expression in malaria-endemic regions.
Complement Receptor Type 1 (CR1) is a malaria-associated gene that encodes a transmembrane receptor of erythrocytes and is crucial for malaria parasite invasion. The expression of CR1 contributes to the rosetting of erythrocytes in the brain bloodstream, causing cerebral malaria, the most severe for...
Հիմնական հեղինակներ: | , , , , , |
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Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
Public Library of Science (PLoS)
2023-01-01
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Շարք: | PLoS ONE |
Առցանց հասանելիություն: | https://doi.org/10.1371/journal.pone.0280282 |