Population-specific positive selection on low CR1 expression in malaria-endemic regions.

Complement Receptor Type 1 (CR1) is a malaria-associated gene that encodes a transmembrane receptor of erythrocytes and is crucial for malaria parasite invasion. The expression of CR1 contributes to the rosetting of erythrocytes in the brain bloodstream, causing cerebral malaria, the most severe for...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Paolo Alberto Lorenzini, Elena S Gusareva, Amit Gourav Ghosh, Nurul Adilah Binte Ramli, Peter Rainer Preiser, Hie Lim Kim
التنسيق: مقال
اللغة:English
منشور في: Public Library of Science (PLoS) 2023-01-01
سلاسل:PLoS ONE
الوصول للمادة أونلاين:https://doi.org/10.1371/journal.pone.0280282