Analysis of the Protective Immunity Induced by Herpes Simplex Virus 1 Strain M3 with an Attenuated Phenotype Due to Mutations in the Viral ul7, ul41, and LAT Genes

Analysis of the Protective Immunity Induced by Herpes Simplex Virus 1 Strain M3 with an Attenuated Phenotype Due to Mutations in the Viral ul7, ul41, and LAT Genes

Herpes simplex virus 1 (HSV1) is an important pathogen with a worldwide epidemic trend that affects populations of various ages. It has a high morbidity, particularly in juveniles, but a successful HSV1 vaccine is not currently available. Thus, our study systematically observed the immune responses...

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Bibliographic Details
Main Authors: Xingli Xu, Shengtao Fan, Xi Wang, Yunguang Hu, Min Feng, Lichun Wang, Ying Zhang, Yun Liao, Xiaolong Zhang, Qihan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Microbiology
Subjects:
herpes simplex virus 1 (HSV1)
protective immunity
M3
ul7
ul41
LAT
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01958/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01958/full

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