Homer 1 gene products orchestrate Ca2+-permeable AMPA receptor distribution and LTP expression
We studied the role of Homer1 gene products on the presence of synaptic Ca2+-permeable AMPA receptors (AMPARs) and LTP generation in hippocampal CA1 pyramidal neurons, using mice that either lacked all Homer1 isoforms (Homer1 KO) or overexpressed the immediate early gene product Homer1a (H1aTG). We...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-09-01
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Series: | Frontiers in Synaptic Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnsyn.2012.00004/full |