Keratocan Improves Muscle Wasting in Sarcopenia by Promoting Skeletal Muscle Development and Fast‐Twitch Fibre Synthesis

Keratocan Improves Muscle Wasting in Sarcopenia by Promoting Skeletal Muscle Development and Fast‐Twitch Fibre Synthesis

ABSTRACT Background Osteosarcopenia refers to the co‐occurrence of osteoporosis and sarcopenia, which are characterized by progressive bone density and muscle mass loss, respectively. Muscle and bone are regulated by many common genes and pathways, enabling potential co‐treatment. Because keratocan...

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Bibliographic Details
Main Authors: Xu Chen, Yanyan Zhang, Zhibo Deng, Chao Song, Linhai Yang, Rongsheng Zhang, Peng Zhang, Yu Xiu, Yibin Su, Jun Luo, Jie Xu, Hanhao Dai
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
keratocan
osteoporosis
osteosarcopenia
PI3K/AKT/mTOR pathway
sarcopenia
Online Access:https://doi.org/10.1002/jcsm.13724

Internet

https://doi.org/10.1002/jcsm.13724

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