Discovery and validation of molecular biomarkers for colorectal adenomas and cancer with application to blood testing.

BACKGROUND & AIMS:Colorectal cancer incidence and deaths are reduced by the detection and removal of early-stage, treatable neoplasia but we lack proven biomarkers sensitive for both cancer and pre-invasive adenomas. The aims of this study were to determine if adenomas and cancers exhibit charac...

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Bibliographic Details
Main Authors: Lawrence C LaPointe, Susanne K Pedersen, Robert Dunne, Glenn S Brown, Letitia Pimlott, Snigdha Gaur, Aidan McEvoy, Melissa Thomas, David Wattchow, Peter L Molloy, Graeme P Young
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3261845?pdf=render