RAB4A GTPase regulates epithelial-to-mesenchymal transition by modulating RAC1 activation

Abstract Epithelial-to-mesenchymal transition (EMT) is a critical underpinning process for cancer progression, recurrence and resistance to drug treatment. Identification of new regulators of EMT could lead to the development of effective therapies to improve the outcome of advanced cancers. In the...

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Bibliographic Details
Main Authors: Subbulakshmi Karthikeyan, Patrick J. Casey, Mei Wang
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Breast Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13058-022-01564-6