Rhodopsin gene expression determines rod outer segment size and rod cell resistance to a dominant-negative neurodegeneration mutant.

Rhodopsin gene expression determines rod outer segment size and rod cell resistance to a dominant-negative neurodegeneration mutant.

Two outstanding unknowns in the biology of photoreceptors are the molecular determinants of cell size, which is remarkably uniform among mammalian species, and the mechanisms of rod cell death associated with inherited neurodegenerative blinding diseases such as retinitis pigmentosa. We have address...

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Bibliographic Details
Main Authors: Brandee A Price, Ivette M Sandoval, Fung Chan, Ralph Nichols, Ramon Roman-Sanchez, Theodore G Wensel, John H Wilson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3503812?pdf=render

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http://europepmc.org/articles/PMC3503812?pdf=render

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