Low-dose decitabine-intensified modified conditioning regimen alleviates aGVHD in AML/MDS patients treated with allogeneic hematopoietic stem cell transplantation

Low-dose decitabine-intensified modified conditioning regimen alleviates aGVHD in AML/MDS patients treated with allogeneic hematopoietic stem cell transplantation

BackgroundThe widespread adoption of Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT) has significantly improved the survival rates of patients with hematological malignancies. However, Graft-Versus-Host Disease (GVHD) remains a formidable complication, threatening patient prognosis. R...

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Bibliographic Details
Main Authors: Jinye Zhu, Qingya Wang, Hanyun Ren, Yujun Dong, Yue Yin, Qian Wang, Zeyin Liang, Wei Liu, Qingyun Wang, Bingjie Wang, Yuan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
low-dose decitabine
conditioning regimen
AML/MDS
allogeneic hematopoietic stem cell transplantation
graft versus host disease
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1274492/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1274492/full

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