Chronic temporal lobe epilepsy is associated with enhanced Alzheimer-like neuropathology in 3×Tg-AD mice.

Chronic temporal lobe epilepsy is associated with enhanced Alzheimer-like neuropathology in 3×Tg-AD mice.

The comorbidity between epilepsy and Alzheimer's disease (AD) is a topic of growing interest. Senile plaques and tauopathy are found in epileptic human temporal lobe structures, and individuals with AD have an increased incidence of spontaneous seizures. However, why and how epilepsy is associa...

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Bibliographic Details
Main Authors: Xiao-Xin Yan, Yan Cai, Jarod Shelton, Si-Hao Deng, Xue-Gang Luo, Salvatore Oddo, Frank M Laferla, Huaibin Cai, Gregory M Rose, Peter R Patrylo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3498246?pdf=render

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http://europepmc.org/articles/PMC3498246?pdf=render

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