Macrophage RIPK3 triggers inflammation and cell death via the XBP1–Foxo1 axis in liver ischaemia–reperfusion injury

Macrophage RIPK3 triggers inflammation and cell death via the XBP1–Foxo1 axis in liver ischaemia–reperfusion injury

Background & Aims: Receptor-interacting serine/threonine-protein kinase 3 (RIPK3) is a central player in triggering necroptotic cell death. However, whether macrophage RIPK3 may regulate NOD1-dependent inflammation and calcineurin/transient receptor potential cation channel subfamily M membe...

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Bibliographic Details
Main Authors: Xiaoye Qu, Tao Yang, Xiao Wang, Dongwei Xu, Yeping Yu, Jun Li, Longfeng Jiang, Qiang Xia, Douglas G. Farmer, Bibo Ke
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:JHEP Reports
Subjects:
ER stress
Innate immunity
IRE1α
XBP1
Foxo1
Reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923002100

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http://www.sciencedirect.com/science/article/pii/S2589555923002100

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