Lessons Learned from Targeting IGF-I Receptor in Thyroid-Associated Ophthalmopathy

Complex immunological mechanisms underlie the pathogenesis of thyroid-associated ophthalmopathy (TAO). Historical models of Graves’ disease and TAO have focused almost entirely on autoimmune reactivity directed against the thyrotropin receptor (TSHR). The insulin-like growth factor-I receptor (IGF-I...

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Bibliographic Details
Main Authors: Joseph A.M.J.L. Janssen, Terry J. Smith
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/2/383