Carbonic Anhydrase 1-Mediated Calcification Is Associated With Atherosclerosis, and Methazolamide Alleviates Its Pathogenesis

Carbonic Anhydrase 1-Mediated Calcification Is Associated With Atherosclerosis, and Methazolamide Alleviates Its Pathogenesis

Vascular calcification is an important pathogenic process in atherosclerosis (AS); however, its immediate cause is unknown. Our previous study demonstrated that carbonic anhydrase 1 (CA1) stimulates ossification and calcification in ankylosing spondylitis and breast cancer. The current study investi...

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Bibliographic Details
Main Authors: Lin Yuan, Minghua Wang, Tianqi Liu, Yinsheng Lei, Qiang Miao, Quan Li, Hongxing Wang, Guoqing Zhang, Yinglong Hou, Xiaotian Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pharmacology
Subjects:
carbonic anhydrase 1
calcification
atherosclerosis
acetazolamide
methazolamide
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00766/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00766/full

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