Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal EpitheliumSummary

Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal EpitheliumSummary

Background & Aims: NF-E2-related factor 2 (NRF2) is a transcription factor that regulates cytoprotective gene expression in response to oxidative and electrophilic stresses. NRF2 activity is mainly controlled by Kelch-like ECH-associated protein 1 (KEAP1). Constitutive NRF2 activation by NRF...

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Bibliographic Details
Main Authors: Wataru Hirose, Makoto Horiuchi, Donghan Li, Ikuko N. Motoike, Lin Zhang, Hafumi Nishi, Yusuke Taniyama, Takashi Kamei, Mikiko Suzuki, Kengo Kinoshita, Fumiki Katsuoka, Keiko Taguchi, Masayuki Yamamoto
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Cell Competition
DNA Damage
Replication Stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X22001965

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http://www.sciencedirect.com/science/article/pii/S2352345X22001965

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