The astrocyte-targeted therapy by Bushi for the neuropathic pain in mice.

BACKGROUND: There is accumulating evidence that the activation of spinal glial cells, especially microglia, is a key event in the pathogenesis of neuropathic pain. However, the inhibition of microglial activation is often ineffective, especially for long-lasting persistent neuropathic pain. So far,...

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Bibliographic Details
Main Authors: Keisuke Shibata, Takeshi Sugawara, Kayoko Fujishita, Youichi Shinozaki, Takashi Matsukawa, Tsutomu Suzuki, Schuichi Koizumi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3158083?pdf=render