CLSPCOL rescues Alzheimer’s disease mouse models

Calmodulin-like skin protein (CLSP) inhibits Alzheimer’s disease (AD)-related neurotoxicity. The activity of CLSP is reduced in AD. To restore the CLSP activity, we developed a hybrid peptide named CLSPCOL, consisting of CLSP(1–61) and the collagen-homologous region (COL) of adiponectin. It was prev...

Full description

Bibliographic Details
Main Authors: Kusakari Shinya, Nawa Mikiro, Hashimoto Yuichi, Matsuoka Masaaki
Format: Article
Language:English
Published: De Gruyter 2022-02-01
Series:Translational Neuroscience
Subjects:
Online Access:https://doi.org/10.1515/tnsci-2022-0209