Salicylate Sodium Suppresses Monocyte Chemoattractant Protein-1 Production by Directly Inhibiting Phosphodiesterase 3B in TNF-α-Stimulated Adipocytes

Salicylate Sodium Suppresses Monocyte Chemoattractant Protein-1 Production by Directly Inhibiting Phosphodiesterase 3B in TNF-α-Stimulated Adipocytes

As a worldwide health issue, obesity is associated with the infiltration of monocytes/macrophages into the adipose tissue causing unresolved inflammation. Monocyte chemoattractant protein-1 (MCP-1) exerts a crucial effect on obesity-related monocytes/macrophages infiltration. Clinically, aspirin and...

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Bibliographic Details
Main Authors: Xiaoyu Zhang, Yuan Gao, Zhuangzhuang Liu, Wenjing Li, Yuan Kang, Ximeng Li, Zhenlu Xu, Cheng Peng, Yun Qi
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
cAMP
MKP-1
p-ERK
p-p38
metaflammation
Online Access:https://www.mdpi.com/1422-0067/24/1/320

Internet

https://www.mdpi.com/1422-0067/24/1/320

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