Multigene profiles to guide the use of neoadjuvant chemotherapy for breast cancer: a Copenhagen Breast Cancer Genomics Study

Abstract Estrogen receptor (ER) and human epidermal growth factor 2 (HER2) expression guide the use of neoadjuvant chemotherapy (NACT) in patients with early breast cancer. We evaluate the independent predictive value of adding a multigene profile (CIT256 and PAM50) to immunohistochemical (IHC) prof...

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Bibliographic Details
Main Authors: M.-B. Jensen, C. B. Pedersen, M.-A. Misiakou, M.-L. M. Talman, L. Gibson, U. B. Tange, H. Kledal, I. Vejborg, N. Kroman, F. C. Nielsen, B. Ejlertsen, M. Rossing
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-023-00551-0