Feasibility, safety and preliminary efficacy of preoperative stereotactic radiotherapy on the future pancreatic neck transection margin to reduce the risk of pancreatic fistula after high-risk pancreatoduodenectomy (FIBROPANC): protocol for a multicentre, single-arm trial

Introduction Postoperative pancreatic fistula (POPF) occurs in 25% of patients undergoing a high-risk pancreatoduodenectomy (PD) and is a driving cause of major morbidity, mortality, prolonged hospital stay and increased costs after PD. There is a need for perioperative methods to decrease these ris...

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Bibliographic Details
Main Authors: Joanne Verheij, Michail Doukas, Bas Groot Koerkamp, Erwin van der Harst, Arantza Fariña, Geertjan van Tienhoven, J. Annelie Suurmeijer, Leonoor V. Wismans, Tessa E. Hendriks, Anna M. Bruynzeel, Joost J. Nuyttens, Martijn P.W. Intven, Lydi M.J.W. van Driel, Olivier R. Busch, Jaap J. Stoker, Ignace H.J. de Hingh, Daan J. Lips, Marc G. Besselink, Casper H.J. van Eijck
Format: Article
Language:English
Published: BMJ Publishing Group 2024-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/14/9/e087193.full