Clinical Impact of the Line Probe Assay and Xpert® MTB/RIF Assay in the Presumptive Diagnosis of Drug-Resistant Tuberculosis in Brazil: A Pragmatic Clinical Trial

Clinical Impact of the Line Probe Assay and Xpert® MTB/RIF Assay in the Presumptive Diagnosis of Drug-Resistant Tuberculosis in Brazil: A Pragmatic Clinical Trial

ABSTRACT Background: Rapid molecular methods such as the line probe assay (LPA) and Xpert® MTB/RIF assay (Xpert) have been recommended by the World Health Organization for drug-resistant tuberculosis (DR-TB) diagnosis. We conducted an interventional trial in DR-TB reference centers in Brazil to ev...

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Bibliographic Details
Main Authors: Afranio Kritski, Maria Martha Oliveira, Isabela Neves de Almeida, Daniela Ramalho, Monica Kramer de Noronha Andrade, Monica Carvalho, Pryscila Fernandes Campino Miranda, Margareth Pretti Dalcolmo, Jose Ueleres Braga, Tania Brígido, Eliene Mesquita, Claudia Dias, Aglae Gambirasio, Joao Baptista Souza Filho, Anne Detjen, Patrick Peter John Phillips, Ivor Langley, Paula Fujiwara, Stephen Bertel Squire
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2022-02-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Tuberculosis
Diagnostics
Impact assessment
Molecular tests
MDR-TB
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000100301&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000100301&tlng=en

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