Angiotensin-converting enzyme 2 identifies immuno-hot tumors suggesting angiotensin-(1–7) as a sensitizer for chemotherapy and immunotherapy in breast cancer

Angiotensin-converting enzyme 2 identifies immuno-hot tumors suggesting angiotensin-(1–7) as a sensitizer for chemotherapy and immunotherapy in breast cancer

Abstract Background Angiotensin-converting enzyme 2 (ACE2) is known as a tumor suppressor and lowly expressed in most cancers. The expression pattern and role of ACE2 in breast cancer (BC) have not been deeply elucidated. Methods A systematic pan-cancer analysis was conducted to assess the expressio...

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Bibliographic Details
Main Authors: Jie Mei, Yun Cai, Rui Xu, Xinqian Yu, Xu Han, Miaomiao Weng, Lingyan Chen, Tao Ma, Tianshu Gao, Fei Gao, Tiansong Xia, Yichao Zhu, Yan Zhang
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Biological Procedures Online
Subjects:
ACE2
Breast cancer
Tumor microenvironment
Ang-1–7
Immunotherapy
Online Access:https://doi.org/10.1186/s12575-022-00177-9

Internet

https://doi.org/10.1186/s12575-022-00177-9

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