SP-8356: A Novel Verbenone Derivative Exerts In Vitro Anti-Non-Small Cell Lung Cancer Effects, Promotes Apoptosis via The P53/MDM2 Axis and Inhibits Tumor Formation in Mice
Objective: Non-small cell lung cancer (NSCLC) stands as a prominent contributor to cancer-related fatalities on aglobal scale, necessitating the search for novel therapeutic agents. SP-8356, a derivative of (1S)-(–)-verbenone, hasshown promise as an anticancer agent in preclinical studies. However,...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Royan Institute (ACECR), Tehran
2023-12-01
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Series: | Cell Journal |
Subjects: | |
Online Access: | https://www.celljournal.org/article_708579_c87d2189c52ec6f2507082100d2b06f0.pdf |