SP-8356: A Novel Verbenone Derivative Exerts In Vitro Anti-Non-Small Cell Lung Cancer Effects, Promotes Apoptosis via The P53/MDM2 Axis and Inhibits Tumor Formation in Mice

Objective: Non-small cell lung cancer (NSCLC) stands as a prominent contributor to cancer-related fatalities on aglobal scale, necessitating the search for novel therapeutic agents. SP-8356, a derivative of (1S)-(–)-verbenone, hasshown promise as an anticancer agent in preclinical studies. However,...

Full description

Bibliographic Details
Main Authors: Lei Yang, Liyi Hu
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2023-12-01
Series:Cell Journal
Subjects:
Online Access:https://www.celljournal.org/article_708579_c87d2189c52ec6f2507082100d2b06f0.pdf