Differential expression of brain cannabinoid receptors between repeatedly stressed males and females may play a role in age and gender-related difference in traumatic brain injury: Implications from animal studies

Differential expression of brain cannabinoid receptors between repeatedly stressed males and females may play a role in age and gender-related difference in traumatic brain injury: Implications from animal studies

Inconsistent gender differences in the outcome of TBI have been reported. The mechanism is unknown. In a recent male animal study, repeated stress followed by TBI had synergistic effects on brain gene expression and caused greater behavioral deficits. Because females are more likely to develop anxie...

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Bibliographic Details
Main Authors: Guoqiang eXing, Janis eCarlton, Xiaolong eJiang, Jillian eWen, Min eJia, He eLi
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Neurology
Subjects:
Amygdala
Hippocampus
Hypothalamus
Prefrontal Cortex
Cannabinoid receptor
epigenetics
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00161/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00161/full

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