Molecular Mechanisms that Regulate Epidermal Growth Factor Receptor Inactivation
The Epidermal Growth Factor Receptor (EGFR) is the prototypical receptor tyrosine kinase (RTK). These cell surface receptors are integral membrane proteins that bind ligands on their extracellular domain and relay that information to within the cell. The activated EGFR regulates diverse cell fates s...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2008-01-01
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Series: | Clinical Medicine Insights: Oncology |
Online Access: | https://doi.org/10.4137/CMO.S498 |