Analysis of cardiovascular dynamics in pulmonary hypertensive C57BL6/J mice

Analysis of cardiovascular dynamics in pulmonary hypertensive C57BL6/J mice

A computer model was used to analyze data on cardiac and vascular mechanics from C57BL6/J mice exposed to 0 (n = 4), 14 (n = 6), 21 (n = 8) and 28 (n = 7) days of chronic hypoxia and treatment with the VEGF receptor inhibitor SUGEN (HySu) to induce pulmonary hypertension. Data on right ventricular p...

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Bibliographic Details
Main Authors: Shivendra eTewari, Scott eBugenhagen, Zhijie eWang, David eSchreier, Brian eCarlson, Naomi eChesler, Daniel eBeard
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Physiology
Subjects:
stress
cardiac mechanics
pulmonary hypertension
Strain
myofiber
re-modeling.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00355/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00355/full

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