Impaired synaptic plasticity in an animal model of autism exhibiting early hippocampal GABAergic-BDNF/TrkB signaling alterations

Summary: In Neurodevelopmental Disorders, alterations of synaptic plasticity may trigger structural changes in neuronal circuits involved in cognitive functions. This hypothesis was tested in mice carrying the human R451C mutation of Nlgn3 gene (NLG3R451C KI), found in some families with autistic ch...

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Detaylı Bibliyografya
Asıl Yazarlar: Martina Sgritta, Beatrice Vignoli, Domenico Pimpinella, Marilena Griguoli, Spartaco Santi, Andrzej Bialowas, Grzegorz Wiera, Paola Zacchi, Francesca Malerba, Cristina Marchetti, Marco Canossa, Enrico Cherubini
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Elsevier 2023-01-01
Seri Bilgileri:iScience
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2589004222020016