Iron content of glioblastoma tumours and role of ferrous iron in the hypoxic response in vitro

Iron content of glioblastoma tumours and role of ferrous iron in the hypoxic response in vitro

IntroductionGlioblastomas are an aggressive primary brain cancer, characterised by hypoxia and poor patient survival. Iron is the most abundant transition metal in the brain, yet data on the iron content of brain cancers is sparse. Ferrous iron is an essential cofactor for a super-family of enzymes,...

Full description

Bibliographic Details
Main Authors: Citra Praditi, Eira Beverley-Stone, Malcolm Reid, Eleanor R. Burgess, Rebekah L. Crake, Margreet C.M. Vissers, Janice A. Royds, Tania L. Slatter, Gabi U. Dachs, Elisabeth Phillips
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Oncology
Subjects:
brain cancer
survival
elemental iron
ferrous iron
hypoxia
glioblastoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1536549/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2025.1536549/full

Similar Items