PRRSV Non-Structural Proteins Orchestrate Porcine E3 Ubiquitin Ligase RNF122 to Promote PRRSV Proliferation

PRRSV Non-Structural Proteins Orchestrate Porcine E3 Ubiquitin Ligase RNF122 to Promote PRRSV Proliferation

Ubiquitination plays a major role in immune regulation after viral infection. An alternatively spliced porcine E3 ubiquitin ligase RNF122 promoted PRRSV infection and upregulated in PRRSV-infected PAM cells was identified. We characterized the core promoter of RNF122, located between −550 to −470 bp...

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Bibliographic Details
Main Authors: Ruiqi Sun, Yanyu Guo, Xiaoyang Li, Ruiqiao Li, Jingxuan Shi, Zheng Tan, Lilin Zhang, Lei Zhang, Jun Han, Jinhai Huang
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Viruses
Subjects:
RNF122
porcine reproductive and respiratory syndrome virus (PRRSV)
nsp1
nsp4
nsp
ubiquitination
Online Access:https://www.mdpi.com/1999-4915/14/2/424

Internet

https://www.mdpi.com/1999-4915/14/2/424

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