Independent domains for recruitment of PRC1 and PRC2 by human XIST.
XIST establishes inactivation across its chromosome of origin, even when expressed from autosomal transgenes. To identify the regions of human XIST essential for recruiting heterochromatic marks we generated a series of overlapping deletions in an autosomal inducible XIST transgene present in 8p of...
| Главные авторы: | , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
Public Library of Science (PLoS)
2021-03-01
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| Серии: | PLoS Genetics |
| Online-ссылка: | https://doi.org/10.1371/journal.pgen.1009123 |