Differential Changes in Akt and AMPK Phosphorylation Regulating mTOR Activity in the Placentas of Pregnancies Complicated by Fetal Growth Restriction and Gestational Diabetes Mellitus With Large-For-Gestational Age Infants

Differential Changes in Akt and AMPK Phosphorylation Regulating mTOR Activity in the Placentas of Pregnancies Complicated by Fetal Growth Restriction and Gestational Diabetes Mellitus With Large-For-Gestational Age Infants

Background: Dysregulation of placental mechanistic target of rapamycin (mTOR) activity has been implicated in the pathophysiology of pregnancies complicated by idiopathic fetal growth restriction (FGR) and gestational diabetes mellitus (GDM) with large-for-gestational-age (LGA) infants. However, the...

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Bibliographic Details
Main Authors: Tai-Ho Hung, Chung-Pu Wu, Szu-Fu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Medicine
Subjects:
placenta
fetal growth restriction
gestational diabetes mellitus
AMP-activated protein kinase
phosphoinositide 3-kinase
Akt
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.788969/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.788969/full

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