Structure-activity relationship data and ligand-receptor interactions identify novel agonists consistent with sulfakinin tissue-specific signaling in Drosophila melanogaster heart

Structure-activity relationship data and ligand-receptor interactions identify novel agonists consistent with sulfakinin tissue-specific signaling in Drosophila melanogaster heart

Background: The structures and activities of invertebrate sulfakinins that influence gut motility and heart rate are like the vertebrate cholecystokinin (CCK) peptides. Typical of sulfakinin precursors Drosophila melanogaster encodes non-sulfated drosulfakinin I (nsDSK I; FDDYGHMRF-NH2) and nsDSK II...

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Bibliographic Details
Main Authors: Ruthann Nichols, Chloe Bass, Chris Katanski
Format: Article
Language:English
Published: IMR Press 2022-05-01
Series:Frontiers in Bioscience-Landmark
Subjects:
cholecystokinin
fmrfamide-related peptide
Online Access:https://www.imrpress.com/journal/FBL/27/5/10.31083/j.fbl2705150

Internet

https://www.imrpress.com/journal/FBL/27/5/10.31083/j.fbl2705150

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