Inactivation of capsaicin-sensitive nerves reduces pulmonary remodeling in guinea pigs with chronic allergic pulmonary inflammation

Pulmonary remodeling is an important feature of asthma physiopathology that can contribute to irreversible changes in lung function. Although neurokinins influence lung inflammation, their exact role in the extracellular matrix (ECM) remodeling remains to be determined. Our objective was to investig...

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Bibliographic Details
Main Authors: C.M. Prado, G.Z. da Rocha, E.A. Leick-Maldonado, C.M. Starling, V.L. Capelozzi, M.A. Martins, I.F.L.C. Tibério
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2011-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000200007&lng=en&tlng=en